Publications

1. H Ghafouri*, T Lazar*, A Del Conte, LG Tenorio Ku, P Tompa, SCE Tosatto, AM Monzon. (2024) PED in 2024: improving the community deposition of structural ensembles for intrinsically disordered proteins

   Nucleic acids research 52 (D1), D536-D544; *contributed equally
    

2. MC Aspromonte, MV Nugnes, F Quaglia, A Bouharoua, DisProt Consortium, SCE Tosatto, D Piovesan. (2024) DisProt in 2024: improving function annotation of intrinsically disordered proteins.

   Nucleic Acids Research 52 (D1), D434-D441
    

3. G Bianchi, M Mangiagalli, D Ami, J Ahmed, ..., P Tompa, S Brocca. (2024) Condensation of the N-terminal domain of human topoisomerase 1 is driven by electrostatic interactions and tuned by its charge distribution.
   International Journal of Biological Macromolecules, 254, 127754
    
4. MA Diallo, S Pirotte, ..., P Tompa, JL Sussman, A Vanderplasschen. (2023) A fish herpesvirus highlights functional diversities among Zα domains related to phase separation induction and A-to-Z conversion.
   Nucleic Acids Research, 51(2), p. 806-830
    
5. B Mészáros, ..., P Tompa, W Vranken, SCE Tosatto, NE Davey. (2023) Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions.
   Nature Methods, 20(9):1291-1303.
    
6. Z Sárkány, F Rocha, A Bratek-Skicki, P Tompa, S Macedo-Ribeiro, PM Martins. (2023) Quantification of Surface Tension Effects and Nucleation-and-Growth Rates during Self-Assembly of Biological Condensates.
   Advanced Science, 10(23):e2301501
    
7. A Meszaros, J Ahmed, G Russo, P Tompa, T Lazar. (2022) The evolution and polymorphism of mono-amino acid repeats in androgen receptor and their regulatory role in health and disease.
   Frontiers in Medicine, 9:1019803
    
8. T Lazar, A Tantos, P Tompa, E Schad. (2022) Intrinsic protein disorder uncouples affinity from binding specificity.
   Protein Science, 31(11):e4455
    
9. A Bratek-Skicki, M Van Nerom, D Maes, P Tompa. (2022) Biological colloids: Unique properties of membraneless organelles in the cell.
   Adv Colloid Interface Sci, 310:102777
    
10. E Korkmazhan, P Tompa, AR Dunn. (2021) The role of ordered cooperative assembly in biomolecular condensates.
    Nature Reviews Molecular Cell Biology, 22(10):647-648
     
11. J Ahmed, A Meszaros, T Lazar, P Tompa. (2021) DNA-binding domain as the minimal region driving RNA-dependent liquid-liquid phase separation of androgen receptor.
    Protein Science, 30(7):1380-1392

1. MV Nerom, J Ahmed, T Lazar, JV Lindt, R Pancsa, D Maes, P Tompa. (2024) C9orf72-linked arginine-rich dipeptide repeats aggravate pathological phase separation of G3BP1.

   bioRxiv, 2023.03. 31.535023
    

2. A Bratek-Skicki, J Ahmed, K Jonckheere, E Peeters, K Heeren, A Volkov, J Hendrix, P Batys, L Van Den Bosch, P Tompa. (2024) Application of polystyrene sulfonate (PSS) for inhibiting toxicity of ALS/FTD-linked dipeptide repeats.
   bioRxiv, 2023.05. 19.541518
    
3. N Farahi, T Lazar, P Tompa, B Mészáros, R Pancsa. (2024) Phase-separating fusion proteins drive cancer by dysregulating transcription through ectopic condensates.
   bioRxiv, 2023.09. 20.558425
    
4. J Ahmed, JK Claridge, A Meszaros, P Tompa. (2023) Menin regulates androgen receptor-and MLL-driven condensation, upsetting regulation of cellular AR-driven transcription.
   bioRxiv, 2023.08. 04.551977

For the full publication list of the Tompa Lab, click on one of the sources below