Research
ONGOING RESEARCH PROJECTS
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Biomolecular condensates of intrinsically disordered proteins
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F/YGG-motif is an intrinsically disordered nucleic-acid binding motif
The role of ordered cooperative assembly in biomolecular condensates
LLPS affects self-aggregation and seeded aggregation of TDP-43 LCD
Studying the kinetics of LLPS under near-native conditions
LLPS of C9orf72 dipeptide eepeats perturbs stress granule dynamics
Macromolecular interactions and liquid-liquid phase separation of the human androgen receptor
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Proteomics systems biology data integration to contrast the healthy and pathogenic cellular regulation of pathways
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Macromolecular modeling and systematic analysis of IDPs & IDP complexes
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IDPs uncouple affinity from binding specificity
Challenges in describing the dynamics of proteins with ambiguous behavior
PED 4.0: a DB for the conformational ensembles of IDPs
Coevolutionary signals in IDP complexes
Distance-based metrics for comparing IDP ensembles
Interaction between the scaffold proteins CBP by IQGAP1
IDPs enable functional diversity while minimizing promiscuity
CBP-ID3 transiently interacts with an IDR of ZFP106 while remaining 'fuzzy'
Harnessing spider and gecko glues for biotechnological applications
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COMPLETED RESEARCH PROJECTS
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Novel purification strategies for IDPs
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Structural & functional study on ERD (Early Response to Dehydration) plant proteins
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Regulated protein degradation in the ubiquitin-proteasome system
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Structure-based modulation of the calpastatin-calpain interaction
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